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| DOI： |
| 中文关键词: 湿润烧伤膏 慢性糖尿病足溃疡 富血小板血浆 Bates-Jensen评分 创面 |
| 英文关键词:Moisturizing burn ointment Chronic diabetes foot ulcer Platelet rich plasma Bates Jensen rating wound |
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| 摘要点击次数: 11 |
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| 中文摘要: |
| 目的 研究分析湿润烧伤膏联合PRP(富血小板血浆)治疗Wagner 2-3级慢性糖尿病足溃疡的临床疗效。方法 选取2021年4月至2023年4月收治的86例Wagner 2-3级慢性糖尿病足溃疡患者作为研究对象,按照不同治疗方法将其分为试验组(43例)与对照组(43例),给予试验组患者局部创面进行湿润烧伤膏联合PRP治疗,对照组患者局部创面单纯进行PRP治疗,对比两组患者创面Bates-Jensen评分、血清炎症因子变化情况以及临床疗效。结果 治疗7、14 d后,试验组患者创面Bates-Jensen评分(32.14±3.21)分、(23.57±2.75)分,明显低于对照组患者创面Bates-Jensen评分(35.90±3.60)分、(26.77±3.02)分(P均＜0.05)；治疗7d后,两组IL-6、TNF-α和CRP水平均明显下降(P＜0.05),试验组水平明显低于对照组(P＜0.05)。治疗28d后,试验组创面愈合总有效率明显高于对照组(P＜0.05)。结论 湿润烧伤膏联合PRP可有效提高Wagner 2-3级慢性糖尿病足溃疡的治疗效果,减轻机体炎症反应,提高临床疗效,临床应用价值较高。 |
| 英文摘要: |
| Objective To study and analyze the clinical efficacy of MEBO combined with PRP (platelet rich plasma) in the treatment of Wagner 2-3 grade chronic diabetes foot ulcer. Methods From April 2021 to April 2023, 86 patients with Wagner 2-3 grade chronic foot ulcer of diabetes were selected as the research object. They were divided into the test group (43 cases) and the control group (43 cases) according to different treatment methods. The local wounds of the patients in the test group were treated with MEBO combined with PRP. The local wounds of the patients in the control group were treated with PRP alone. The Bates Jensen score of the wounds, changes in serum inflammatory factors and clinical efficacy of the two groups were compared. After 7 and 14 days of treatment, the Bates Jensen scores (32.14 ± 3.21) and (23.57 ± 2.75) of the experimental group patients were significantly lower than those of the control group patients (35.90 ± 3.60) and (26.77 ± 3.02) (both P<0.05); After 7 days of treatment, the levels of IL-6, TNF - α, and CRP in both groups decreased significantly (P<0.05), and the levels in the experimental group were significantly lower than those in the control group (P<0.05). After 28 days of treatment, the total effective rate of wound healing in the experimental group was significantly higher than that in the control group (P<0.05). Conclusion MEBO combined with PRP can effectively improve the therapeutic effect of Wagner 2-3 chronic diabetes foot ulcer, reduce the inflammatory reaction of the body, improve the clinical efficacy, and have high clinical application value. |
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