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下肢静脉性溃疡复发的危险因素分析
Analysis of Risk Factors for Recurrence of Venous Leg Ulcers

陈国庆,李胜宾,刘文曾.下肢静脉性溃疡复发的危险因素分析[J].中国烧伤创疡杂志,2025,(3):181~184.

DOI：

英文关键词:Venous leg ulcer Recurrence Risk factor Body mass index Venous thromboembolism

基金项目:

作者	单位
陈国庆	250022 山东济南, 济南市市中区人民医院外一科
李胜宾
刘文曾

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中文摘要:

【摘要】目的探讨下肢静脉性溃疡 (VLU) 复发的相关危险因素。方法选取 2019 年 1 月至 2023 年 2 月济南市市中区人民医院收治的 334 例 VLU 患者作为研究对象, 收集患者性别、年龄、体重指数 (BMI)、是否吸烟以及合并静脉血栓栓塞 (简称血栓栓塞) 等资料, 并根据溃疡复发情况将其分为复发组和未复发组, 应用多因素 Logistic 回归分析筛选 VLU 复发的相关危险因素。结果随访 2~ 17 个月, 334 例 VLU 患者溃疡复发 89 例(26.65%), 设为复发组; 未复发 245 例 (73.35%), 设为未复发组。多因素 Logistic 回归分析结果显示, BMI 及溃疡面积较大、合并有血栓栓塞是 VLU 复发的独立危险因素 (95%CI 为 1.024 ~ 1.206、1.053 ~ 1.209、3.486 ~ 62.381, P= 0.012、P= 0.001、P<0.001), 且当 BMI≥24.37 kg / m 2 或溃疡面积≥23.52 cm 2 时 VLU 复发的风险显著增加。结论 VLU 的复发与 BMI、是否合并血栓栓塞以及溃疡面积密切相关。

英文摘要:

【Abstract】 Objective To study the risk factors for the recurrence of venous leg ulcers (VLU). Methods 334 patients with VLU admitted to Jinan Shizhong People’s Hospital from January 2019 to February 2023 were selected as research subjects. Data of these subjects were collected, including sex, age, body mass index (BMI), smoking history, and with venous thromboembolism (thromboembolism for short) or not. Based on ulcer recurrence, the patients were divided into the recurrence group and the non?recurrence group. Multivariate Logistic regression was conducted to analyze the risk factors for VLU recurrence. Results During the follow?up of 2-17 months, of the 334 patients with VLU, 89 cases (26.65%) developed ulcer recurrence, being set as recurrence group, and the other 245 cases ( 73.35%) without ulcer recurrence were set as non?recurrence group. Multivariate Logistic regression analysis showed that higher BMI, larger ulcer area, and complicated with thromboembolism were independent risk factors for VLU recurrence ( 95% CI: 1.024 - 1.206, 1.053 - 1.209, 3.486- 62.381, P = 0.012, P = 0.001, P < 0.001). The risk of VLU recurrence significantly increased when BMI ≥24.37 kg / m 2 or ulcer area ≥23.52 cm 2 . Conclusion The recurrence of VLU was closely associated with BMI, the presence of thromboembolism, and ulcer area.